β -caryophyllene and β -caryophyllene oxide-natural compounds of anticancer and analgesic properties
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منابع مشابه
β‐caryophyllene and β‐caryophyllene oxide—natural compounds of anticancer and analgesic properties
Natural bicyclic sesquiterpenes, β-caryophyllene (BCP) and β-caryophyllene oxide (BCPO), are present in a large number of plants worldwide. Both BCP and BCPO (BCP(O)) possess significant anticancer activities, affecting growth and proliferation of numerous cancer cells. Nevertheless, their antineoplastic effects have hardly been investigated in vivo. In addition, both compounds potentiate the c...
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The n-hexane extract of S. salignus plants inhibited ATP synthesis and two sesquiterpenes, the β-caryophyllene (1) and caryophyllene oxide (2) were isolated from this nonpolar fraction. Compound 1 inhibited by 42% the root elongation of Physalis ixocarpa seedlings at 50 µg/mL and by 53% at 150 µg/mL, whereas at 150 µg/mL this compound only inhibited root elongation of Echinochloa crus-galli by ...
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Increasing evidence suggests that plant-derived extracts and their isolated components are useful for treatment of seizures and, hence, constitute a valuable source of new antiepileptic drugs with improved efficacy and better adverse effect profile. β-Caryophyllene is a natural bicyclic sesquiterpene that occurs in a wide range of plant species and displays a number of biological actions, inclu...
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ژورنال
عنوان ژورنال: Cancer Medicine
سال: 2016
ISSN: 2045-7634
DOI: 10.1002/cam4.816